As applicable, efforts must consider factors for scale-up and efforts to make any instrumentation developed broadly accessible and cost-effective for the end-user. For approaches and technologies developed under this FOA, detailed synthetic protocols and documentation verifying the purity and structures of synthetic products will ultimately need to be provided in order to facilitate cross validation, as required for this Common Fund effort.
This FOA is focused on two areas: 1 development of new methods and technologies for synthesis of biomedically relevant mammalian glycomes; and 2 development of new methods and technologies for synthesis of biomedically relevant microbial glycans that can inform on disease processes.
Examples of applications responsive to this FOA include but are not limited to:. Other Information for award authorities and regulations. Cooperative Agreement: A support mechanism used when there will be substantial Federal scientific or programmatic involvement. Substantial involvement means that, after award, NIH scientific or program staff will assist, guide, coordinate, or participate in project activities. See Section VI. Application budgets should be strongly justified and reflect the actual needs for the proposed project.
Non-domestic non-U. Entities Foreign Institutions are not eligible to apply. Organizations are not eligible to apply. All registrations must be completed prior to the application being submitted. Registration can take 6 weeks or more, so applicants should begin the registration process as soon as possible.
The NIH Policy on Late Submission of Grant Applications states that failure to complete registrations in advance of a due date is not a valid reason for a late submission. Obtaining an eRA Commons account can take up to 2 weeks. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.
Applicant organizations may submit more than one application, provided that each application is scientifically distinct. The NIH will not accept duplicate or highly overlapping applications under review at the same time.
This means that the NIH will not accept:. See your administrative office for instructions if you plan to use an institutional system-to-system solution. Conformance to the requirements in the Application Guide is required and strictly enforced. Applications that are out of compliance with these instructions may be delayed or not accepted for review.
Although a letter of intent is not required, is not binding, and does not enter into the review of a subsequent application, the information that it contains allows IC staff to estimate the potential review workload and plan the review. By the date listed in Part 1. Overview Information , prospective applicants are asked to submit a letter of intent that includes the following information:.
Pamela A. Marino, Ph. Telephone: Fax: Email: marinop nigms. Research Strategy : As part of the Research Strategy Section, applications should clearly address the following aspects:. As such, all applications must address how their proposed resource will make glycoscience more "integrated and accessible" by addressing these definitions:. A milestone is a defined event, achievement, or important stage that is used to indicate the progress of a project.
Milestones should be descriptive of what will be done and when it will be completed. Applicants must provide an implementation plan that includes a general description of what will be needed for cross-validation activities.
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